The designation of the Institute for Biological Products Control (IBPC) of National Institutes for Food and Drug Control (NIFDC) as the WHO Collaborating Center on the standardization and evaluation of biologicals has been successfully renewed, with the term of designation from December 24, 2021 to December 24, 2025. The IBPC has been designated for two consecutive terms since 2013. During the terms, the IBPC has successfully completed various activities in the work plan, including supporting WHO in developing and revising international standards for biologicals, contributing to the development of international standards and reference materials for biologicals, conducting research & development of quality control assays for biologicals, and providing technical assistance in vaccine prequalification, which has been highly recognized by relevant WHO management departments and officials.