MGI Tech's innovative sequencing technology drives mangrove conservation Efforts in Thailand

MGI Tech Co., Ltd. ("MGI"), a  company dedicated to developing core tools and technologies that drive innovation in life sciences, has partnered with National Omics Center (NOC) under the National Science and Technology Development Agency (NSTDA) to leverage advanced sequencing technology for mangrove conservation research. The joint efforts aim to address the environmental challenges facing mangroves, which play a crucial role in coastal defense and the livelihoods of local communities.

For centuries, mangroves have served as nature's coastal guardians, acting as protective and vital barriers against erosion and storm surges while providing a haven for marine species. These ecosystems are crucial to the fishing industry, which contributes significantly to the nation's economy. However, over the past 50 years, more than 60% of Thailand's mangroves have been lost due to deforestation and urban development. With their disappearance comes increased vulnerability to environmental changes, making conservation efforts ever more pressing.

"Mangroves have stood by us," reflected a local fisherman. "They protect us from the waves and give young fish and crabs a place to grow. Without them, our way of life would be at risk."

A Genetic Lens on Mangrove Conservation

Understanding the genetic diversity of mangroves is essential to developing effective conservation strategies. Genetic data reveals how species adapt to challenges such as rising sea levels, changes in salinity, and habitat loss. The MGI sequencer DNBSEQ-G400RS allows for precise evaluation of such diversity for the first time, enabling researchers to delve into this genetic complexity with unprecedented precision, marking significant progress in conservation strategies.

Dr. Jeremy Shearman, Senior Researcher at the NOC, emphasized the value of this approach. "Mangroves are essential for coastal regions and estuaries. They offer erosion protection from surf and storm damage, creating nurseries for young marine life that replenish ocean stocks. Understanding genetic diversity helps us preserve these valuable ecosystems."

He further explained, "The main purpose of the research was for conservation. We wanted to identify the species present, sequence their genomes to create reference databases, and use restriction enzyme sequencing to measure genetic variation across mangrove populations throughout Thailand."

How MGI Tech Empowers the Initiative

At the heart of this initiative is MGI's cutting-edge technology. MGI's proprietary DNBSEQ™ sequencing technology supports Restriction-site Associated DNA sequencing (RAD-seq), which is pivotal in building a comprehensive reference genome database and assessing the genetic diversity of these critical ecosystems. The RAD-seq method efficiently identifies genetic markers, crucial for constructing reference genomes and understanding the genetic diversity among mangrove populations. This insight is fundamental for formulating effective conservation strategies targeting these vital ecosystems.

Dr. Wirulda Pootakham, Director of NOC, remarked, "Building a reference genome database for 15 mangrove species in Thailand allows us to assess genetic diversity more accurately using DNA data. This is vital for prioritizing conservation efforts."

The precision of MGI's sequencing technology is transformative. "MGI's platform delivers high-quality data that reduces uncertainties in our research and allows us to focus on achieving impactful biodiversity outcomes," shared Ms. Sonicha U-thoomporn, Research Assistant at the NOC.

"Our innovative sequencing process offers unmatched accuracy and efficiency, which are critical for biodiversity research, analysis, and conservation," added Mr. Nitinai Sising, MGI Sales Manager, Thailand.

Beyond RAD-seq, RNA sequencing enabled by MGI further enhances this research by revealing gene expression and adaptive mechanisms of mangroves to high-sodium environments. Together, these techniques offer an integrated view of mangrove biodiversity, resilience, and adaptability.